Registration Dossier
Registration Dossier
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EC number: 224-658-5 | CAS number: 4439-24-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
Data source
Reference
- Reference Type:
- other: Expert assessment
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- GLP compliance:
- no
- Type of study:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
Test material
- Reference substance name:
- 2-(2-methylpropoxy)ethanol
- EC Number:
- 224-658-5
- EC Name:
- 2-(2-methylpropoxy)ethanol
- Cas Number:
- 4439-24-1
- Molecular formula:
- C6H14O2
- IUPAC Name:
- 2-(2-methylpropoxy)ethan-1-ol
Constituent 1
Results and discussion
In vivo (non-LLNA)
Results
- Key result
- Remarks on result:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
- Executive summary:
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 2-(2-methylpropoxy)ethanol is not expected to induce skin sensitisation.
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