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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
December 08, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to
Guideline:
other: ASTM D 2879–97 (Standard Test Method for Vapor Pressure-Temperature Relationship and Initial Decomposition Temperature of Liquids by Isoteniscope)
Version / remarks:
2007
Deviations:
yes
Remarks:
A digital electronic pressure gauge was used to measure vapour pressure
Principles of method if other than guideline:
The method used for this experiment was a modified version of the one described in ASTM D 2879 – 97 (2007). Instead of the mercury manometer stipulated for vapour pressure measurement in the ASTM method, a digital electronic pressure gauge was used.
GLP compliance:
no
Type of method:
isoteniscope
Specific details on test material used for the study:
Purity test date: 20/10/2017
Expirty date: 18/04/2018
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
< 0.75 mm Hg
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
< 0.75 mm Hg
Test no.:
#3
Temp.:
20 °C
Vapour pressure:
< 0.75 mm Hg
Key result
Temp.:
20 °C
Vapour pressure:
< 0.75 mm Hg

Results

Vapour Pressure at

20 °C

(mm Hg)

Run 1

< 0.75

Run 2

< 0.75

Run 3

< 0.75

Average

< 0.75

Conclusions:
The vapour pressure of 2-(2-methylpropoxy)ethanol was determined to be <0.75 mm Hg (<1.00 hPa) at 20 °C.
Executive summary:

To determine the vapour pressure of 2-(2-methylpropoxy)ethanol, an experiment was performed according to a technique similar / equivalent to ASTM D 2879–97 (Standard Test Method for Vapor Pressure-Temperature Relationship and Initial Decomposition Temperature of Liquids by Isoteniscope). A deviation was reported in which a digital electronic pressure gauge was used to measure vapour pressure rather than the mercury manometer stipulated in the protocol. This difference is believed to be acceptable and not likely to significantly impact the final result. The experiment was performed in triplicate. The average vapour pressure of 2-(2-methylpropoxy)ethanol was calculated to be <0.75 mm Hg, converted to <1.00 hPa (2 d.p.), at 20 °C.

Description of key information

A vapour pressure of <0.75 mm Hg (<1.00 hPa) was obtained for 2-(2-methylpropoxy)ethanol at 20 °C.

Key value for chemical safety assessment

Vapour pressure:
1 hPa
at the temperature of:
20 °C

Additional information

An experiment was performed using a method equivalent to ASTM D 2879-97 (Standard Test Method for Vapor Pressure-Temperature Relationship and Initial Decomposition Temperature of Liquids by Isoteniscope). A deviation from the protocol was reported, specifically that a digital electronic pressure gauge was used as opposed to the mercury manometer stipulated for pressure measurement, however, this was deemed to be acceptable. This gave a key value for vapour pressure that has been considered to be suitable for chemical safety assessment. A Klimisch score of 1 (reliable without restriction) is subsequently recommended.