Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data from handbook; no guideline or method described.
GLP compliance:
not specified
Test type:
other: Not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
>= 200 - <= 400 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Conclusions:
Based on an dermal LD50 range of 200-400 mg/kg bw for rabbit, the substance meets the criteria for classification as Acute toxicity Category 3 via dermal route in accordance with Regulation (EC) N° 1272/2008.
Executive summary:

A dermal LD50 of 200 -400 mg/kg bw for rabbit was reported in a toxicology handbook. No inforamtion on the test method was given. Based on the reported values the substance meets the criteria for Acute toxicity Category 3 via the dermal route in accordance with Regulation (EC) N° 1272/2008.