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Diss Factsheets

Administrative data

Link to relevant study record(s)

oxidising liquids
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
August 21, 2017
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The molecular structure (functionality) and composition of 2-(2-methylpropoxy)ethanol was reviewed in line with relevant regulation in order to determine the oxidising potential of the substance.
no guideline followed
Principles of method if other than guideline:
The oxidising potential of 2-(2-methylpropoxy)ethanol was estimated based on the molecular structure (functionality) and composition of the material. The REACH Regulation (EC) No. 1907/2006 and the CLP Regulation (EC) No. 1272/2008 were referred to in order to screen for relevant properties within the substance known to react exothermically and cause, or contribute to, the combustion of other material, typically by yielding oxygen.
GLP compliance:
Key result
Sample tested:
other: Not applicable
other: Expert assessment / oxidising properties
Remarks on result:
other: 2-(2-Methylpropoxy)ethanol does not have oxidising potential.
Interpretation of results:
GHS criteria not met
An assessment was undertaken to determine the oxidising potential of 2-(2-methylpropoxy)ethanol. Given a lack of structural features associated with oxidising behaviour, such as halogens, nitrogen, or metals, it has been concluded that the registration substance is not an oxidising agent and does not require classification.
Executive summary:

The oxidising potential of 2-(2-methylpropoxy)ethanol was reviewed through expert assessment of information and experimental data related to the molecular structure, functionality, and composition of the substance. A screening procedure was employed in line with the REACH Regulation (EC) No. 1907/2006 and the CLP Regulation (EC) No. 1272/2008 in order to identify any exothermic properties of the liquid that may, by yielding oxygen, cause or contribute to the combustion of other material and brand 2-(2-methylpropoxy)ethanol an oxidising agent. Halide-oxygen groups, nitrogen-oxygen groups and some metal-oxygen complexes are functional groups that are typical of oxidising agents. It was determined, however, that the raw materials of 2-(2-methylpropoxy)ethanol do not contain nitrogen, metals, or halogens such as chlorine and fluorine, and these elements are not present in the final product. The oxygen that is present within the substance is also chemically bonded to carbon and hydrogen and, therefore, does not pose any risk of reacting exothermically. It can be concluded that 2-(2-methylpropoxy)ethanol does not have oxidising potential and does not require classification. Further testing is not required under Column II of REACH Annex VII.

Description of key information

It was determined by expert assessment that 2-(2-methylpropoxy)ethanol does not possess the elements typical of an oxidising agent, and that the oxygen atoms present within the structure are chemically bonded to carbon and hydrogen. Subsequently, it can be concluded that there is not a risk of oxidising behaviour and the registration substance does not require classification as an oxidising agent. Further testing is not needed (Column II, REACH Annex VII).

Key value for chemical safety assessment

Oxidising properties:
non oxidising

Additional information

The endpoint conclusion obtained for oxidising potential has been assigned a Klimisch score of 2 (reliable with restrictions) given that it has been determined by assessment of a weight of evidence. It is a key value and is considered to be suitable for the purpose of classification and chemical safety assessment.

Justification for classification or non-classification