Registration Dossier
Registration Dossier
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EC number: 202-809-6 | CAS number: 100-00-5
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- 2-Chloronitrobenzene and 4-Chloronitrobenzene: Administered by inhalation to F344/N rats and B6C3F1 mice.
- Author:
- NTP
- Year:
- 1 993
- Bibliographic source:
- Toxicity Report Series No. 33, NIH Publication, 93-3382, July/1993
- Reference Type:
- publication
- Title:
- Effect of dose on the disposition and metabolism of 4-chloronitrobenzene (4-CNB) in male fischer-344 rats following oral administration.
- Author:
- Silveira DM, Markham PM, McComish MF, Nomeir AA, Chadwick M
- Year:
- 1 989
- Bibliographic source:
- The Toxicologist 9(1): 86 (Abstr.)
Materials and methods
- Objective of study:
- toxicokinetics
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-4-nitrobenzene
- EC Number:
- 202-809-6
- EC Name:
- 1-chloro-4-nitrobenzene
- Cas Number:
- 100-00-5
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-4-nitrobenzene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Fischer 344
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- No. of animals per sex per dose / concentration:
- 8
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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