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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Adopted according to OECD SIDS; basic data given (comparable to guidelines)

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1986
Report date:
1986
Reference Type:
secondary source
Title:
1-CHLORO-4-NITROBENZENE CAS No: 100-00-5 SIDS Initial Assessment Report.
Author:
OECD
Year:
2002
Bibliographic source:
UNEP Publications

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 202, part 2 (1984)
Deviations:
yes
Remarks:
; only four concentrations used; counting not made on a daily basis
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1-chloro-4-nitrobenzene
EC Number:
202-809-6
EC Name:
1-chloro-4-nitrobenzene
Cas Number:
100-00-5
Molecular formula:
C6H4ClNO2
IUPAC Name:
1-chloro-4-nitrobenzene
Details on test material:
- Name of test material (as cited in study report): p- chlornitrobenzol
- Analytical purity: 99.7%

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d

Test conditions

Test temperature:
around 20 °C
pH:
8.3 ± 1
Nominal and measured concentrations:
- The following TS concentrations were tested: 0.16, 0.5, 1.58 and 5.0 mg/l
Details on test conditions:
- Per concentration 10 trials were carried out in parallel starting with 1 Daphnia in each vessel
- Control consisted of 20 animals
- Test medium was renewed 3 times a week

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
EC10
Effect conc.:
0.15 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
EC10
Effect conc.:
0.103 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: based on an analytical recovery of 69.2 %
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
2.92 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
2.02 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: based on an analytical recovery of 69.2 %
Details on results:
According to OECD SIDS:
The lowest effect value was a 21d-EC10 of 0.103 mg/l for reproduction of Daphnia magna. This value was calculated from the
nominal EC10 of 0.15 mg/l using the analytical recovery of 69.2 % from the test concentration 1.5 mg/l.

Applicant's summary and conclusion