Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: dermal, other
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
significant methodological deficiencies
Remarks:
Publication with limited reporting details; test substance was administered (skin application) weekly, and only skin section was examined.

Data source

Reference
Reference Type:
publication
Title:
Tests on mice for evaluating carcinogenicity.
Author:
Hodge, H.C., Maynard, E.A., Downs, W.L., Ashton, J.K. and Salerno, L.L.
Year:
1966
Bibliographic source:
Toxicology and applied pharmacology 9, pg.583-596.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(2-ethylhexyl) adipate
EC Number:
203-090-1
EC Name:
Bis(2-ethylhexyl) adipate
Cas Number:
103-23-1
Molecular formula:
C22H42O4
IUPAC Name:
bis(2-ethylhexyl) adipate

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

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