Registration Dossier
Registration Dossier
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EC number: 203-090-1 | CAS number: 103-23-1
Endpoint summary
Administrative data
Description of key information
Additional information
Partitioning of substances into the different environmental compartments depends mainly on their physico-chemical properties. Since the water solubility of Bis(2-ethylhexyl) adipate (DEHA) is very low (0.0032 mg/L) and the log Pow value high (8.94), the substance is expected to mainly distribute to sediment and soil. However, as DEHA and the relevant metabolite 2-ethylhexanoic acid are readily biodegradable according to the OECD criteria, DEHA and its degradation products will not be persistent in the environment.
DEHA is not expected to evaporate into the atmosphere due to the low vapor pressure of < 0.0001 Pa at 20 °C. The more volatile transient metabolites (2-ethylhexanol, 2-ethylhexanal) are assumed to be rapidly oxidized to the respective acid (2-ethylhexanoic acid), which is not considered to be volatile. If entering the atmosphere, DEHA and its metabolites will be rapidly degraded by photochemical processes. Thus, long-range transport through the atmospheric compartment is not expected. This is confirmed by results from the Swedish National Screening Programme 2004 (Remberger et al. 2005). Abiotic hydrolysis is not relevant, since the substance is readily biodegradable and thus expected to be eliminated through biodegradation in natural waters. Additionally, an estimated rate of hydrolysis is low.
Based on the rapid environmental biodegradation and metabolisation via enzymatic hydrolysis, relevant uptake and bioaccumulation in aquatic organisms is not expected. Enzymatic breakdown will initially lead to the free dicarboxylic acid and the free alcohol. From literature it is well known, that these hydrolysis products will be metabolised and excreted in fish effectively (for detailed information please see chapter 5.3 of technical dossiers). This is supported by low BCF values calculated for DEHA and its transient metabolites (BCF << 2000 L/kg ww; BCFBAF v3.01; Arnot-Gobas, including biotransformation, upper trophic).
Remberger et al. 2005. Results from the Swedish National Screening Programme 2004, Subreport 1: Adipates. IVL Report B1645, IVL Swedish Environmental Research Institute
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