Registration Dossier
Registration Dossier
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EC number: 290-754-9 | CAS number: 90218-76-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 3 000 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
Additional information
Experimental studies in rats show a very low acute oral toxicity for 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters. No clinical effects were observed at doses of 3000 mg/kg. Mortalities occurred at doses of 17319 mg/kg and above.
Two acute dermal toxicity studies of 1,2,4 -Benzenetricarboxylic acid, mixed decyl and octyl triesters show also a low dermal toxicity. No mortalities nor clinical effects were observed at the limit dose of 2000 mg/kg.
Based on the available data it can be concluded that 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters is of very low acute oral and dermal toxicity.
Justification for classification or non-classification
Th oral and acute LD50 -values exceed clearly the cut-off value for classification according to Regulation (EC) No 1272/2008.
Overall, the acute oral and dermal toxicity of 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters is low and does not warrant classification.
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