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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Physical & Chemical properties

Partition coefficient

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partition coefficient
Type of information:
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Scientifically acceptable method
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Principles of method if other than guideline:
log octanol-water partition coefficient (log KOW) estimation using an atom/fragment contribution method
GLP compliance:
Type of method:
other: calculation
Partition coefficient type:
Key result
log Pow
Partition coefficient:
20 °C
ca. 7
Log Kow (KOWWIN v1.68 estimate) = 12.79

Description of key information

Log Pow = 12.79 (calculated with KOWWIN from EPI Suite)

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

Due to its hydrophobic structure the experimental determination of the logPow of 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters is not possible as no sufficiently sensitive analytical method is available.

According to REACH Guidance on information requirements and chemical safety assessment Chapter R.7.1.8 highly accurate measurements of high log Pow are not possible and no standard method is available for log Pow > 8.3.

To determine a reliable logPow the value was calculated using the KOWWIN v1.68 software from EPI Suite. With the molecular weight of 574.85 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters falls within the ranges of the log KOWWIN model is valid for of 18.02 to 719.92 (for the training set) and 27.03 to 991.15 (for the validation set).

For 1,2,4-Benzenetricarboxylic acid, decyl octyl ester, the model accounts for each fragment, therefore also for this aspect the substance fits within the domain: Log Kow = 12.79

The calculated logPow for 1,2,4-Benzenetricarboxylic acid, decyl octyl ester is 12.79