3,3'-iminodi(propylamine)

PBT assessment

PBT assessment: overall result

Reference

Name:

3,3'-iminodi(propylamine)

Type of composition:

legal entity composition of the substance

State / form:

liquid

Reference substance:

3,3'-iminodi(propylamine)

PBT status:

the substance is not PBT / vPvB

Justification:

The substance is readily biodegradable based on an CO2 Evolution Test according to OECD 301B. After 28 days of exposure the degree of biodegradation was 89%. Therefore, the substance is not persisitent (not P/vP).

The measured log Kow (-1.25 at 25°C, BASF AG, 1989, report no. BRU 89.022) indicates no potential for bioaccumulation (not B/vB). In addition, BCF values were estimated to be 3.2 L/kg (BCFBAF v3.01, EPI Suite v4.11) and 0.07 L/kg (Bysshe, 1990). Measured read-across data for two structurally analogous substances support the estimated BCF values. In both studies performed according to OECD 305, the BCFs were found to be equal or lower than 6.3 L/kg (CAS 111 -40 -0) and lower than 5 L/kg (CAS 112 -24 -3) (NITE, 2011). Therefore, the substance is not bioaccumulative (not B/vB).

With respect to aquatic toxicity, the substance is "not T " since the lowest available chronic value is > 0.01 mg/L. Experimental chronic toxicity data are available only for algae (72 -h ErC10 > 100 mg/L, BASF AG 1989, report no. 01/0499/2/89) and aquatic invertebrates (21 -d NOEC = 5.6 mg/L, read-across from CAS 111 -40 -0, Akzo 1992, report no. CRL F91183). With respect to mammalian toxicity, the substance is "T", based on the self-classification as STOT-RE, target organ: thymus gland.

Therefore, with respect to all endpoints, the substance is "T".

In summary, the substance can be regarded as not PBT and not vPvB.