Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 200-261-2 | CAS number: 56-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- 3,3'-iminodi(propylamine)
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- 3,3'-iminodi(propylamine)
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance is readily biodegradable based on an CO2 Evolution Test according to OECD 301B. After 28 days of exposure the degree of biodegradation was 89%. Therefore, the substance is not persisitent (not P/vP).
The measured log Kow (-1.25 at 25°C, BASF AG, 1989, report no. BRU 89.022) indicates no potential for bioaccumulation (not B/vB). In addition, BCF values were estimated to be 3.2 L/kg (BCFBAF v3.01, EPI Suite v4.11) and 0.07 L/kg (Bysshe, 1990). Measured read-across data for two structurally analogous substances support the estimated BCF values. In both studies performed according to OECD 305, the BCFs were found to be equal or lower than 6.3 L/kg (CAS 111 -40 -0) and lower than 5 L/kg (CAS 112 -24 -3) (NITE, 2011). Therefore, the substance is not bioaccumulative (not B/vB).
With respect to aquatic toxicity, the substance is "not T " since the lowest available chronic value is > 0.01 mg/L. Experimental chronic toxicity data are available only for algae (72 -h ErC10 > 100 mg/L, BASF AG 1989, report no. 01/0499/2/89) and aquatic invertebrates (21 -d NOEC = 5.6 mg/L, read-across from CAS 111 -40 -0, Akzo 1992, report no. CRL F91183). With respect to mammalian toxicity, the substance is "T", based on the self-classification as STOT-RE, target organ: thymus gland.
Therefore, with respect to all endpoints, the substance is "T".
In summary, the substance can be regarded as not PBT and not vPvB.
Reference
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