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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Significant accumulation in organisms is not to be expected. 

Key value for chemical safety assessment

Additional information

In accordance with column 2 of REACH Annex IX, the study does not need to be conducted since 3,3'-iminodi(propylamine) has a log Kow of less than 3 (experimental log Kow = -1.25 @25°C, BASF AG 1989, report no. BRU 89.022).

Experimental data on the bioaccumulation potential of 3,3'-iminodi(propylamine) are not available. Therefore, the assessment is based on a weight-of-evidence approach by read-across data for two structurally analogous substances, bis(2-aminoethyl)amine (CAS 111-40-0) and TETA (CAS 112-24-3), as well as calculated data for 3,3'-iminodi(propylamine) itself.

Both read-across studies were performed similar to OECD 305, using Cyprinus carpio as test species. The BCF for bis(2-aminoethyl)amine (CAS 111-40-0) was determined to be equal or lower than 6.3 L/kg and the BCF for TETA (CAS 112-24-3) was lower than 5 L/kg (NITE, 2011).

In addition, the BCF of 3,3'-iminodi(propylamine) was estimated to be 3.2 L/kg using BCFBAF v3.01 of EPI Suite v4.11 (submodel Meylan et al. 1997/1999); substance within applicability domain; BASF SE, 2017) and 0.07 L/kg based on the calculation from the octanol-water partition coefficient (Byssche 1990).

In conclusion, significant accumulation in organisms is not to be expected.