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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

 Based on the GHS, no chronic toxicity is anticipated at an NOEC or EC10 > 1 mg/L.

Key value for chemical safety assessment

Additional information

Experimental data on the chronic toxicity of 3,3'-iminodi(propylamine) (CAS 56-18-8) on aquatic invertebrates are not available.

Read-across data on long-term toxicity are available from a GLP study according to EU method C.20 (Daphnia magna reproduction test) with the structural analogous substance DETA (CAS 111-40-0). The 21-d NOEC was determined to be 5.6 mg/L (nominal; Akzo, 1991). The concentrations were not analytically verified during the test, but DETA is expected to be stable, due to a high water solubility (miscible), a moderate vapour pressure (VP = 0.35 Pa @20°C, measured) and a low Henry's Law Constant (HLC = 3.14 E-08 Pa m³/mol @ 25°C, calculated with HENRYWIN v3.20, not in applicability domain).

The key study is supported by an OECD 211 GLP-guideline study (ECHA database entry, without detailed documentation) with the structural analogous substance 1,2 -Ethanediamine, N,N'-bis(2 -aminoethyl)- (CAS 112 -24 -3), providing a 21-d EC10 of 1.9 mg/L.