Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
Chapman & Hall Number: FPT10-V
Author:
Chapman & Hall
Year:
2012
Bibliographic source:
Combined Chemical Dictionary, Version 6.1

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Data is from handbook of 'CCD (Combined Chemical Dictionary)'
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
- Name of test material (as cited in study report): 2'-acetonaphthone
- Substance type: Organic
- Physical state: Solid

Test animals

Species:
human

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Remarks on result:
other: Skin irritant

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance 2'-acetonaphthone gives positive result for skin irritation when applied on human skin.
Executive summary:

The substance 2'-acetonaphthone gives positive result for skin irritation when applied on human skin.