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EC number: 223-453-8 | CAS number: 3900-45-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The estimated inhibition concentration (IC50) of 1-(6-methoxy-2-naphthyl)ethan-1-one for tetrahymena pyriformis for 48 hours using QSAR toolbox version 2.3 is 108.73 mg/l.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 108.73 mg/L
Additional information
Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3900-45-6 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
IC50 |
108.7335 mg/l |
Population |
48 hrs |
Tetrahymena pyriformis |
Predicted data for target chemical |
2 |
IGC50 |
25.04128 mg/l |
growth |
48 hrs
|
Tetrahymena pyriformis |
Predicted data for target chemical |
3 |
IGC50
|
18.3244 mg/l
|
-
|
46 hrs
|
Tetrahymena pyriformis |
Predicted data for target chemical |
4 |
IGC50 |
17 mg/l |
growth inhibition |
48 hrs
|
Tetrahymena pyriformis |
Data from publication for CAS no 93-04-9 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that IGC50 value is expected to be in the range of 17-108.7335 mg/l in 46 to48 hrs study.
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