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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Monographs on fragrance raw materials:beta - NAPHTHYL METHYL ETHER
Author:
Opdyke DLJ
Year:
1975
Bibliographic source:
Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.
Reference Type:
other: Authoritative data base
Title:
GCID : 521659
Author:
ACToR database
Year:
2011
Bibliographic source:
ACToR (Aggregated Computational Toxicology Resource);Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.
Reference Type:
review article or handbook
Title:
RTECS Number: QJ9468750
Author:
RTECS database
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances); Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Data is from Actor and RTECS
GLP compliance:
not specified
Test type:
standard acute method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
- Name of test material (as cited in study report): Methyl 2-naphthyl ether
- Substance type: Organic
- Physical state: solid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
5 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Acute oral toxicity (LD50) value of Methyl-2-naphtyl ether to rat on the basis of mortality was obtained at dose concentration 5000 mg/kg bw .This value indicate that Methyl-2-naphtyl ether is non toxic to rat by oral route.
Executive summary:

Acute oral toxicity (LD50) value of Methyl-2-naphtyl ether to rat on the basis of mortality was obtained at dose concentration 5000 mg/kg bw .This value indicate that Methyl-2-naphtyl ether is non toxic to rat by oral route.