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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Monographs on fragrance raw materials:beta - NAPHTHYL METHYL ETHER
Author:
Opdyke DLJ
Year:
1975
Bibliographic source:
Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.
Reference Type:
other: Authoritative data base
Title:
GCID : 521659
Author:
ACToR database
Year:
2011
Bibliographic source:
ACToR (Aggregated Computational Toxicology Resource);Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.
Reference Type:
review article or handbook
Title:
RTECS Number: QJ9468750
Author:
RTECS database
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances); Food and Cosmetics Toxicology. Vol. 13, Pg. 885, 1975.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is from Actor and RTECS
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl 2-naphthyl ether
EC Number:
202-213-6
EC Name:
Methyl 2-naphthyl ether
Cas Number:
93-04-9
Molecular formula:
C11H10O
IUPAC Name:
2-methoxynaphthalene
Test material form:
solid: crystalline
Details on test material:
- Name of test material (as cited in study report): Methyl 2-naphthyl ether
- Substance type: Organic
- Physical state: solid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
5 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Acute oral toxicity (LD50) value of Methyl-2-naphtyl ether to rat on the basis of mortality was obtained at dose concentration 5000 mg/kg bw .This value indicate that Methyl-2-naphtyl ether is non toxic to rat by oral route.
Executive summary:

Acute oral toxicity (LD50) value of Methyl-2-naphtyl ether to rat on the basis of mortality was obtained at dose concentration 5000 mg/kg bw .This value indicate that Methyl-2-naphtyl ether is non toxic to rat by oral route.