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EC number: 500-051-3
CAS number: 26780-96-1
The test compound, BI0-76-109 FLECTOL H, Lot 5E866, was examined for
mutagenic activity in a series of in vitro microbial assays employing
Salmonella and Saccharomyces-indicator organisms. The compound was
tested directly and in the presence of liver microsomal enzyme
preparations from Aroclor-induced rats. The following results were
The compound was tested over a series of concentrations such that there
was evidence of some chemically-induced physiological
effects at the high dose level. The low dose in all cases was below a
concentration that demonstrated any toxic effect. The dose range
employed for the evaluation of this compound was from 0.5 µg ~ 250 µg
B. Nonactivation Test Results
The results of the tests conducted on the compound in the absence of a
metabolic system were all negative.
C. Activation Test Results
The results of the tests ·conducted on the compound in the presence
of the rat liver activation system were all negative.
The objective of this study was to evaluate the test compound for
genetic activity in microbial assayson Salmonella typhimurium strain
TA98, TA100, TA1535, TA1537, TA1538 and Saccharomyces cerevisiae strain
D4 with and without the addition of mammalian metabolic activation
The test compound, BIO-76-109 FLECTOL H, Lot 5E866, did not demonstrate
mutagenic activity in any of the assays conducted
in this evaluation and was considered not mutagenic under these test
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