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EC number: 500-051-3
CAS number: 26780-96-1
Clinical signs as sluggishness was recorded to start 48 h after dosing;
death occurred during the second to fourth day after treatment
thereafter the animals recoverd. Macroscopic examiation of the survivors
revealed white necrotic spots on the kidney of several rats.
In an early study with limited documentation groups of 5 male and 5
female albino rats were dosed with TMQ in an acute oral toxicity
experiment. Animals were dosed with 2160 to 4470 mg/kg and observed for
14 days. Clinical signs as sluggishness was recorded to start 48 h after
dosing; death occurred during the second to fourth day after treatment.
The calculated LD50 was 3190 mg/kg (95% CL 2730 -3720 mg/kg).
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