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EC number: 252-552-9
CAS number: 35415-27-1
Table #: Irritant/corrosive response
data for each animal at each observation time up to removal of each
animal from the test
Score at time point / Reversibility
Max. score: 4
Average 24h, 48h, 72h
Average time (unit) for reversion
*) Reversibility: c. = completely
reversible; n.c. = not completely reversible; n. = not reversible
To test the acute skin irritant effect,
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters was
applied to shaven dorsal skin of rabbits. The product was administered
undiluted, and the time of exposure in the patch test was 4 hours. The
test was carried out in accordance with OECD guideline 404 (12 May
The test substance showed only a slightly irritating
effect (primary dermal irritation index (PDII): 1.67) on the skin of
male rabbits. Mean erythema scores from 24, 48 and 72 hour readings for
each animal were in between 1 and 2. In two animals mean edema score was
0 and in one animal the mean edema score was 0.3. All animals were free
of symptoms after 6 - 8 days.
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