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EC number: 252-552-9
CAS number: 35415-27-1
The study used as source investigated bacteriotoxicity of
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters
according to a method developed by the testing laboratory. The test
substance did not affect the bacterial respiration and derived effect
concentration were: 4.75h-EC10 > 0.9 g a.i./L, 4.75h-EC50 > 915 -1060 mg
a.i./L (corrected for the molecular weight of the target substance).
Results of the source compound were considered applicable to the target
compound. Justification and applicability of the read-across approach
(structural analogue) is outlined in the read-across report in section
13 or find a link in cross-reference “assessment report”.
No microorganism toxicity data for the submission substance is available. However adequate and reliable data for structural analogues is available (i.e. C8C10TM, for read-across justification please see read-across report in section 13).The derived 4.75h-EC10 (Pseudomonas putida, respiration) > 915 -1060 mg a.i./L (corrected for the molecular weight of the target substance).
No microorganism toxicity data for the submission substance is
available. However adequate and reliable data for structural analogues
(i.e. C8C10TM, for read-across justification please see read-across
report in section 13) are reported below.
In a reliable toxicity study on microorganism (non-guideline study and
in compliance with GLP, Huels AG, 1994, RL2), no effect on respiration
(biochemical oxygen demand) was observed during 4.75 hours of exposure
to three concentrations up to 980 mg a.i./L test substance (nominal 1000
mg/L, use of solubilizer, analogue substance: 1,2,4-benzenetricarboxylic
acid, mixed decyl and octyl triesters, C8C10TM, CAS no. 90218-76-1)
(corresponding to 915 - 1060 mg/L of the target substance). No
analytical verification of the test concentrations was performed. No
toxicity to microorganisms is expected below the water solubility of the
analogue and submission substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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