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EC number: 203-466-5
CAS number: 107-13-1
An anonymous author (Japan MoE, 2011) reports a 48 -hour EC50 of 2.5
mg/L (mean measured) for acrylonitrile in Daphnia magna. This
study was performed on behalf of the Japanese Ministry of the
Environment in accordance with a Japanese national method equivalent to
OECD TG 201 and in compliance with GLP. The test was conducted under
static conditions in Elendt M4 medium with sealed test vessels to limit
volatilisation losses of the test substance and maintain exposure
The Japan MoE (2011) study with D. magna was reliably performed,
with appropriate measures to ensure that exposure to acrylonitrile was
satisfactorily maintained, and is considered to provide the key acute
toxicity endpoint for freshwater invertebrates. The 48 hour EC50
reported in Daphnia magna in four other studies is between 7.6-22
mg/L Neuparth et al. (2011) reported the results of a number of public
domain studies where testing had been conducted on aquatic
invertebrates. The 48-hour LC50 for Artemia salina was reported
to be 14.34 mg/L. The 24 -hour LC50 for Crangon franciscorum was
reported to be 10-33 mg/L.
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