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EC number: 203-466-5
CAS number: 107-13-1
ABS moulding: The results showed very low concentrations
of acrylonitrile. 100% of the results were below the measurement limit
Rubber moulding: The airborne PAHs concentration levels
found in the 19 study subjects were low. Urinary napthalene and urinary
phenanthrene were found to be present in the highest amounts. The other
low-boiling point urinary PAHs, whilst present in most samples, showed
levels below 10 ng/l. High-boiling point urinary PAHs were always found
in amounts lower than the measurement limit. No differences were
observed between smokers and non-smokers.
This study was carried out in the plastic and rubber moulding industry,
in the “Professional Cancer Prevention Project” with the objective of
developing and implementing protocols for evaluating exposure to
carcinogens through the biological monitoring. The carcinogenic
substances identified were: 1,3-butadiene, acrylonitrile and styrene in
moulding ABS, and polycyclic aromatic hydrocarbons (PAH) in moulding
rubber. Only for some of these substances biological indicators are
available. The limited exposure to airborne chemicals in moulding ABS
and the intrinsic characteristics of biological indicators available for
1-3 butadiene have determined the non-applicability of biological
monitoring to this situation. Exposure in the rubber moulding was
studied in 19 subjects applying the determination not metabolized PAH in
urine. The levels of these indicators were similar to those measured in
other groups of subjects without occupational exposure to PAH,
confirming a low airborne contamination in this workplace.
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