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Diss Factsheets
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EC number: 243-053-7 | CAS number: 19430-93-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no emission to STP expected
Sediment (freshwater)
- Hazard assessment conclusion:
- no exposure of sediment expected
Sediment (marine water)
- Hazard assessment conclusion:
- no exposure of sediment expected
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no exposure of soil expected
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
In well conducted aquatic toxicity studies on fish, daphnia and algae, PFBE showed no toxicity at the highest concentrations achievable (maxium loading rate 1000mg/l). Thus no hazard has been identified and no PNEC is derivied.
Though not readily biodegradable, PFBE (3,3,4,4,5,5,6,6,6-nonafluorohexene) is not likely to persist in surface waters due to its low water solubility (15.6 mg/l), high vapour pressure (22kPa at 20°C) and estimated Henry's Law constant (3 - 100 atm.m3.mol-1). As a result, releases of PFBE to the aquatic environment are likely to rapidly partition to atmosphere, and detectible concentrations in water will be hard to acheive. PFBE has only moderate affinity for soil (measured log Koc = 2.96 Koc = 903). Volatilisation from wet and dry soil surfaces is expected to be an important fate process, based on the estimated Henry's law constant and this compound's high vapour pressure. Any PFBE released into the environment is expected to partition almost entirely to the atmosphere, where it will quickly react with atmospheric hydoxyl radicals (°OH), with a short atmospheric lifetime, estimated to be 6.4 hours.
Moreover, direct and indirect exposure of the aquatic compartment, sediment and soil is considered unlikely (See the document PFBE: REACH Annex IX waivers for Degradation and Fate and Behaviour in the Environment. Blue Frog Scientific Limited. Attached to Section 5 Summary Environmental Fate and Pathways).
Conclusion on classification
In well conducted aquatic toxicity studies on fish, daphnia and algae, PFBE showed no toxicity at the highest concentrations achievable (maximum loading rate 1000mg/l). Thus no hazard has been identified and no PNEC is derived.Therefore PFBE does not need to be classified as Dangerous for the Environment in Acute Category 1 or Chronic Categories 1,2, or 3 according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008. Although PFBE is not rapidly degradable, the extreme volatility of the substance would result in near complete volatilisation, coupled with rapid atmospheric degradation, ensuring that the substance is rapidly removed from the aquatic compartment and degraded from the environment as a whole. In conclusion PFBE meets the “rapidly degradable” criteria set for non-classification as Chronic Category 4 due to its ultimate environmental fate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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