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EC number: 212-990-3 | CAS number: 903-19-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: Range finding test for Study acc. to OECD 305
- Principles of method if other than guideline:
- Deviation from test plan: the amount of feed in the test plan was 2% of the fish weight, but it was actually 1.5%.
- GLP compliance:
- not specified
- Remarks:
- Range finding test for GLP Study acc. to OECD 305
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Oryzias latipes
- Details on test organisms:
- TEST ORGANISM
- Common name: Japanese rice fish
- Source: bred at testing facility
- Length at study initiation (length definition, mean, range and SD): 2 ± 1 cm
- Weight at study initiation (mean and range, SD): ca. 0.2 g
ACCLIMATION
- Acclimation period: 6 wk
- Acclimation conditions (same as test or not): flow-through conditions
- Type and amount of food during acclimation: Tertramin fishfood (Tetra)
- Feeding frequency during acclimation: dayil, approx. 1.5 % of the body weight (no feeding 24 hours before the test)
- Health during acclimation (any mortality observed): <5% dead fish during 1 week before test (no medication of fish)
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Test temperature:
- 24± 1 °C
- Nominal and measured concentrations:
- 5 mg/L
- Details on test conditions:
- TEST SYSTEM
details on test system are not available
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Yokohama city tap water was dechlorinated by activated carbon filtration and sodium thiosulfate addition and used as test water. - Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- not specified
Reference
Description of key information
Not acutely toxic to fish
Key value for chemical safety assessment
Additional information
The assessment of the acute toxicity to fish is based on the results of a range finding study performed in the framework of a bioaccumulation study following OECD 305. Fish of the species Oryzias latipes were exposed to a substance concentration of 5 mg/L in a 96 hour flow-through test. Mortalities were not observed. The determined LC50 (96 h) was >5 mg/L.
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