Registration Dossier
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EC number: 212-990-3 | CAS number: 903-19-5
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Temp.:
- ca. 20 °C
- Vapour pressure:
- ca. 0 Pa
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
Reference
The vapour pressure of AF-317 was determined following EU A.4 using the effusion method
(weight loss).
Vapour pressure was examined at five different temperatures. Four temperatures could be
evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted
against log (P).
For the test item AF-317, the following vapour pressures at 20 °C and at 25 °C were calculated
from the regression equation:
Vapour pressure at 20 °C: 2.01 * 10-05Pa
Vapour pressure at 25 °C: 4.69 * 10-05Pa
Vapour Pressures (Effusion Method) |
||||
Experiment |
T |
Mean P |
Stand. Dev. P |
RSD P |
No. |
K |
Pa |
Pa |
% |
1 |
318.2 |
1.05E-03 |
2.98E-04 |
28.5 |
2 |
333.2 |
9.34E-03 |
1.14E-03 |
12.2 |
3 |
348.2 |
5.87E-02 |
3.61E-03 |
6.2 |
4 |
363.2 |
3.46E-01 |
3.21E-02 |
9.3 |
The vapour pressure of the test item AF-31 7 was determined at five different temperatures(30, 45, 60. 75 and 90 °C) following EU A.4 using the effusion method (weight loss). Experiment 1(nominal temperature 30 °C) showed no reproducible weight loss. Therefore it was not used for calculation of the result.
Four experiments could be evaluated as they showed relevant and reproducible weightloss. All evaluated experiments showed good reproducibility, giving relative standard deviations of less than 29 % and very good correlation.
Therefore, the result of the test can be considered valid.
Description of key information
Approximately 2.01E-5 Pa at 20 °C, approximately 4.69E-5 Pa at 50 °C (OECD 104, effusion method, Knudsen cell)
Key value for chemical safety assessment
Additional information
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