Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Chlorendic Anhydride was found to be irritating to skin, eyes and respiratory system.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Classification

   GHS / CLP  DSD
 Skin corrosion / irritation

 Skin mild irrit.3; H316: causes mild skin irritation. However the substance received a Harmonised Classification as Skin Irrit 2; H315.

Considering it is not allowed to use a classification less severe than the Harmonised Classification, the substance is therefore classified as Skin Irrit 2; H315.

 Xi; R36/37/38 irritating to eyes respiratory system and skin.
 Eye irritation  Eye irritant 2A; H319: causes serious eye irritation   Xi; R36/37/38 irritating to eyes respiratory system and skin.
 Skin sensitisation  Skin sens.1; H317: may cause an allergic skin reaction   Xi; R36/37/38 irritating to eyes respiratory system and skin.



Effects on skin irritation/corrosion: slightly irritating

Effects on eye irritation: highly irritating

Effects on respiratory irritation: irritating

Justification for classification or non-classification

Chlorendic Anhydride is classified as highly irritating to eyes and irritating to the respiratory system but would not be considered a primary skin irritant or a corrosive material. The test material could be further classified, based upon the scores obtained as being slightly irritating to the skin.

 The substance received a Harmonised Classification as Skin Irrit 2; H315. Considering it is not allowed to use a classification less severe than the Harmonised Classification, the substance is therefore classified as Skin Irrit 2; H315.