Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 203-856-5 | CAS number: 111-30-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable data
Data source
Reference
- Reference Type:
- publication
- Title:
- Work-related asthma among health care workers: surveillance data from California, Massachusetts, Michigan, and New Jersey, 1993-1997
- Author:
- Pechter E, Davis LK, Tumpowsky C, Flattery J, Harrison R, Reinisch F, Reilly MJ, Rosenman KD, Schill D P, Valiante D, Filios M
- Year:
- 2 005
- Bibliographic source:
- Am. J. Ind. Med. 47: 265-275
Materials and methods
- Study type:
- health record, other
- Remarks:
- health care workers
- Endpoint addressed:
- respiratory sensitisation
- Principles of method if other than guideline:
- Work-related asthma cases were identified using physician reports and hospital discharge data, as part of four state-based surveillance systems. Structured interviews were used to confirm cases and identify occupations and exposures associated with work-related asthma.
- GLP compliance:
- no
- Remarks:
- ; not applicable
Test material
- Reference substance name:
- Glutaral
- EC Number:
- 203-856-5
- EC Name:
- Glutaral
- Cas Number:
- 111-30-8
- Molecular formula:
- C5H8O2
- IUPAC Name:
- glutaraldehyde
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Glutaraldehyde
Method
- Type of population:
- occupational
- Details on study design:
- Work-related asthma cases were identified using physician reports and hospital discharge data, as part of four state-based surveillance systems. Structured interviews were used to confirm cases and identify occupations and exposures associated with work-related asthma.
Results and discussion
- Results:
- Health care workers (N=305) accounted for 16% of the 1,879 confirmed work-related cases, but only 8% of the states´ workforce.
The number and percentage of work-related asthma cases among health care workers for glutaraldehyde was 27 cases, 9% respectively.
Applicant's summary and conclusion
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
