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EC number: 203-856-5
CAS number: 111-30-8
Glutaraldehyde is acute toxic to fish.
The acute toxicity of glutaraldehyde
50% to rainbow trout (Salmo gairdneri) was tested according to U.S. EPA
Guideline at 0, 1.7, 2.8, 4.6, 7.8, 13 and 22 mg a.i./l (EG & G,
Bionomics BW-81-12-1055). The testing of the acute toxicity of
glutaraldehyde to rainbow trout under static conditions resulted in a
LC50 after 96 hours of 10 mg a.i./l.
The acute toxicity of glutaraldehyde on
Bluegill (Lepomis macrochirus) was investigated at nominal
concentrations of 0, 7.8, 13, 22, 36, 60 and 100 mg a.i./l (EG & G,
Bionomics BW-81-11-1047). The static testing of the acute toxicity of
glutaraldehyde to Bluegill resulted in a LC50 after 96 hours of 13 mg
a.i./l. Symptoms of toxicity occurred from 13 mg a.i./l.
The acute toxicity of
glutaraldehyde was also tested on the marine fish species, sheepshead
minnows (Cyprinodon variegatus) according to an in-house Laboratory Test
Protocol for Fishes (EG & G, Bionomics BP-81-11-178). The testing of the
acute toxicity of glutaraldehyde under static conditions resulted in a
LC50 after 96 hours of 39 mg a.i./l. Symptoms of toxicity occurred at 36
The key studies are based on the nominal concentrations and hence
deviation of more than 20% from the nominal concentration cannot be
excluded. Therefore, the studies based on the nominal concentrations are
recalculated according to TWA concept assuming a DT50dis of 10.6 hours.
The resulting LC50 values were 0.8, 1.0 nad 6.2 mg/L for Salmo
gairdneri, Lepomis macrochirus and Cyprinodon variegatus.
In conclusion, glutaraldehyde is acute
toxic to fish.
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