Registration Dossier
Registration Dossier
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EC number: 203-856-5 | CAS number: 111-30-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Glutaraldehyde is acute toxic to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 10 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 39 mg/L
Additional information
The acute toxicity of glutaraldehyde 50% to rainbow trout (Salmo gairdneri) was tested according to U.S. EPA Guideline at 0, 1.7, 2.8, 4.6, 7.8, 13 and 22 mg a.i./l (EG & G, Bionomics BW-81-12-1055). The testing of the acute toxicity of glutaraldehyde to rainbow trout under static conditions resulted in a LC50 after 96 hours of 10 mg a.i./l.
The acute toxicity of glutaraldehyde on Bluegill (Lepomis macrochirus) was investigated at nominal concentrations of 0, 7.8, 13, 22, 36, 60 and 100 mg a.i./l (EG & G, Bionomics BW-81-11-1047). The static testing of the acute toxicity of glutaraldehyde to Bluegill resulted in a LC50 after 96 hours of 13 mg a.i./l. Symptoms of toxicity occurred from 13 mg a.i./l.
The acute toxicity of
glutaraldehyde was also tested on the marine fish species, sheepshead
minnows (Cyprinodon variegatus) according to an in-house Laboratory Test
Protocol for Fishes (EG & G, Bionomics BP-81-11-178). The testing of the
acute toxicity of glutaraldehyde under static conditions resulted in a
LC50 after 96 hours of 39 mg a.i./l. Symptoms of toxicity occurred at 36
mg a.i./l.
The key studies are based on the nominal concentrations and hence deviation of more than 20% from the nominal concentration cannot be excluded. Therefore, the studies based on the nominal concentrations are recalculated according to TWA concept assuming a DT50dis of 10.6 hours. The resulting LC50 values were 0.8, 1.0 nad 6.2 mg/L for Salmo gairdneri, Lepomis macrochirus and Cyprinodon variegatus.
In conclusion, glutaraldehyde is acute toxic to fish.
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