Registration Dossier
Registration Dossier
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EC number: 203-856-5 | CAS number: 111-30-8
Endpoint summary
Administrative data
Description of key information
Additional information
The terrestrial toxicity was assessed with several terrestrial organism from different biological organization levels.The acute toxicity of glutaraldehyde to earthworms (Eisenia foetida) showed a LC50 value of 170 mg a.i./kg dry weight soil.
A phytotoxicity study was carried out for determination of glutaraldehyde effects on higher plants (Avena sativa,Brassica napus and Vicia sativa). Vicia sativa was the most sensitive species. The respective EC50 and NOEC were 1219 mg a.i./kg dw and 169 mg a.i./kg dw and converted to organic matter content of 3.4%.
The adverse effects of glutaraldehyde on aerobic soil microorganisms were investigated by means of the carbon transformation test (OECD 217) and of the nitrate production test (OECD 216). The carbon transformation test resulted in an EC50 after 28 days of 1045 mg a.i./kg dry matter soil. The nitrate transformation test resulted in an EC50 after 28 days of 546 mg a.i./kg dry matter soil. The acute toxicity of glutaraldehyde 50% to mallard ducks showed an LD50 value of 206 mg a.i./kg bw indicating that glutaraldehyde is moderately toxic to birds. However, since the test substance is not bioaccumulative, secondary poisoning is not a relevant exposure route for birds. Concerning effects of glutaraldehyde to terrestrial arthropods no information is available; since glutaraldehyde is readily biodegradable a direct exposure of soil organisms is unlikely; therefore, no further tests on terrestrial organisms are required.Since data on acute toxicity to soil macroorganisms (earthworm, Eisenia fetida), terrestrial plants (tomato and radish seeds) and carbon as well as nitrate transformation test are available, the EC10 of 10.45 mg a.i./kg dry matter soil for toxicity on carbon transformation microorganisms was used for the calculation of the PNEC soil.
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