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Long-term toxicity to aquatic invertebrates

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Description of key information

NOEC (21 d) = 1.8 mg/L (meas., initial; Daphnia magna; OECD 211)

Key value for chemical safety assessment

Additional information

One study according to OECD 211 (GLP) is available on the long-term toxicity of methyl octanoate (CAS No. 111-11-5) to aquatic invertebrates (Höger, 2013). Due to the low water solubility of the test substance, a 100 mg/L dispersion was first prepared, stirred for 3 hours and filtered. The test organism Daphnia magna was then exposed to dilutions of 1:200, 1:63, 1:20, 1:6.3 and 1:2 of the filtrate, for 21 days. Actual concentrations were quantified by GC/FID analysis. At the two highest concentrations, no offspring were produced due to the mortality of the parent animals. At the three remaining concentrations, no significant mortality and no effect on reproduction were observed. The dilution of 1:20 therefore corresponds to the NOEC (21 d), which was shown to be 1.8 mg/L (measured initial).