Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 204-424-9 | CAS number: 120-78-5
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- other: literature summary
- Rationale for reliability incl. deficiencies:
- other: literature summary of additional toxicological information
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Leaching of antioxidants and vulcanization accelerators from rubber closures into drug preparations
- Author:
- Airaudo, C., B.; et al.
- Year:
- 1 990
- Bibliographic source:
- J. Biomater. Sci. Polymer Edn., vol. 4, 231-241
- Reference Type:
- publication
- Title:
- Toxicity of rubber
- Author:
- Aktulga, A.1972
- Bibliographic source:
- Eczacilik Bulteni (Instanbul) vol. 14, 35-43
- Reference Type:
- publication
- Title:
- Development and application of an LC-MS method to determine possible migration of mercaptobenzothiazole, benzothiazole and related vulcanization residues from rubber used in contact with food and drink
- Author:
- Barnes, K., A., et al.
- Year:
- 2 003
- Bibliographic source:
- Food Additives and Contaminants, vol. 20, no. 2, 196-205
- Reference Type:
- publication
- Title:
- Chemical changes in rubber allergens during vulcanization
- Author:
- Bergendorff, O.; et al.
- Year:
- 2 007
- Bibliographic source:
- Contact Dermatitis 57, 152-157
- Reference Type:
- publication
- Title:
- Effect of sufur-containing compounds on experimental diabetes.
- Author:
- Chiba, T.
- Year:
- 1 969
- Bibliographic source:
- Yakugaku Zasshi, 89 (8), 1138-1143
- Reference Type:
- publication
- Title:
- Oxidation of 2-mercaptobenzothiazole in latex gloves and its possible haptenation pathway
- Author:
- Chipinda, I.; et al.
- Year:
- 2 007
- Bibliographic source:
- Chem. Res. Toxicol., 20, 1084-1092
- Reference Type:
- publication
- Title:
- Mercaptobenzothiazole allergenicity role of the thiol group
- Author:
- Chipinda, I.
- Year:
- 2 008
- Bibliographic source:
- cutaneous and Ocular Toxicology, 27, 103- 116
- Reference Type:
- publication
- Title:
- A carcinogenic potency database of standardized results of animal bioassays
- Author:
- Gold, L., S.; et al.
- Year:
- 1 984
- Bibliographic source:
- Environmental Health Perspectives, vol 58, 9-319
- Reference Type:
- publication
- Title:
- The effect of some heterocyclic disulfides and thiones on the carboxydrate metabolism of Ehrich ascites tumors
- Author:
- Grassetti, D., R.; et al.
- Year:
- 1 970
- Bibliographic source:
- J. Med. Chem., 13(2), 273-276
- Reference Type:
- publication
- Title:
- Extraction of mercaptobentothiazole compounds from rubber products
- Author:
- Hansson, C.; et al.
- Year:
- 1 997
- Bibliographic source:
- Contact Dermatitis, 36, 195-200
Materials and methods
- Type of study / information:
- literature summary of additional toxicological information
- Principles of method if other than guideline:
- literature summary of additional toxicological information
Test material
- Reference substance name:
- Di(benzothiazol-2-yl) disulphide
- EC Number:
- 204-424-9
- EC Name:
- Di(benzothiazol-2-yl) disulphide
- Cas Number:
- 120-78-5
- Molecular formula:
- C14H8N2S4
- IUPAC Name:
- di(benzothiazol-2-yl) disulphide
Constituent 1
Results and discussion
Any other information on results incl. tables
literature summary of additional toxicological information
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
