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EC number: 204-424-9
CAS number: 120-78-5
No short-term or long-term toxicity on three toxonomic groups of three
trophic levels in the aquatic compartment of MBTS was observed up to its
water solubility (i.e. <0.05 mg/L).
Thus, no hazard could be identified.
The short-term toxicity and long-term toxicity of MBTS was tested on
three trophic levels. The concentrations tested were always higher than
its water solubility (i.e. <0.05 mg/L) and precipitation in test vessels
were often reported. No acute ot chronic toxic effect of MBTS on three
taxonomic groups of three trophic levels was observed up to water
For the assessment of microorganisms in biological treatment plants, an
EC50 > 10000 mg/l was observed after 3 hours exposure at a pH 7.5 - 8.3
and temperature of 20.5 - 22.4 °C (Bayer AG, 1990). To the nitrification
inhibition by 2,2'-disulfanediylbis(1,3-benzothiazole) an EC75 of 38
mg/L during a 2 - 4 h incubation period was obtained. (Tomlinson, Boon,
and Trotman, 1966). As the most sensitive value, the effective
concentration on nitrification inhibition is used for further
assessment. MBTS is hydrolytically stable (Hasson & Agrup, 1993). The
transformation of MBTS to MBT (CAS: 149-30-4) requires reductive
condition and the formation of benzothiazole (BT) and benzothiazolone
(BTon) requires high temperature (>60°C) and high pH (>9); and hence
these potential metabolites of MBTS are considered to be not relevant in
the ecotoxicity studies of MBTS
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