Registration Dossier

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
Repeated Insult Patch Test Modified Shelanski (4 x 4 Method)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
SH-82-009, 2,2'-dithio-bis-benzothiazole

Method

Type of population:
general
Controls:
test substance 70% in petrolatum
Route of administration:
dermal

Results and discussion

Results of examinations:
0/53 volunteers with positive skin reactions

Any other information on results incl. tables

the test substance was negative in the Repeated Insult Patch Test (0/53 volunteers with positive skin reactions)

Applicant's summary and conclusion