Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

A study was performed according to the OECD guideline 301 F “Ready biodegradability: Manometric Respirometry Test” in order to assess the ready biodegradability of the test item.
Under the test conditions, the percentage of biodegradation of N,N’-Diphenyl Thiourea reached 0 %of the ThOD at the end of the test (28 days), thus N,N’-Diphenyl Thiourea is not readily biodegradable.
N,N’-Diphenyl Thiourea did not inhibit the micro-organisms as shown by the toxicity control flask where biodegradation percentage is 38% higher than 25 % within 14 days.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The purpose of this study was to assess the ready biodegradability of the test item according to the OECD guideline 301 F “Ready biodegradability: Manometric Respirometry Test”.

According to the OECD guideline 301, the pass level for ready biodegradability is 60% of Theoretical Oxygen Demand (ThOD). This level has to be reached in a 10-d window within the 28-d period of the test. The 10-d window begins when the degree of biodegradation has reached 10% of ThOD and must end before day 28 of the test.

Under the test conditions, the percentage of biodegradation of N,N’-Diphenyl Thiourea reached 0% of the ThOD at the end of the test (28 days).

According to OECD guideline 301F, N,N’-Diphenyl Thiourea is not readily biodegradable.

N,N’-Diphenyl Thiourea did not inhibit the micro-organisms as shown by the toxicity control flask where biodegradation percentage is 38% higher than 25% within 14 days.