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EC number: 203-004-2
CAS number: 102-08-9
Table 1: parent immobilization and mean number of living neonate produced per surviving parents at the end of the test for each concentration tested (expressed as geometric means).
Mean number of neonates
Parent immobilization (%)
Table 2: mean number of neonates (living and dead), eggs and dead parent per day
Table 3: total number of neonates (living and dead), eggs and dead parents
This study was designed to determine the effects of 1,3
-diphenyl-2 -thiourea on Daphnia magna reproduction and survival
in a 21 days test according to the OECD 211 Guideline. The total test
period was 21 days; all test solutions (including control) were renewed
every day (including "weekend" periods). Ten replicate test vessels were
prepared for the control and the test concentration. A single juvenile Daphnia
magna (<24 hours old selected by filtration) was added to each test
vessel. Each day, parental animals were transferred into freshly
prepared test media. Dead parents were noted and discarded. All produced
juveniles were counted every day. Chemical analysis of test samples
confirmed the stability of the substance over a 24-hour test period.
Based on these results, the exposure concentrations were based on the
nominal concentration. NOEC and LOEC values on day 21 were determined as
NOEC for mean number of neonate produced per parent alive at the end of
the test: 0.15 mg/L
NOEC for mobility: 1.56 mg/L
NOEC for age at first reproduction: > 5 mg/L.
The chronic toxicity was assessed according to the OECD 211 guideline.21d-NOEC = 0.15 mg/L.
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