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EC number: 203-004-2
CAS number: 102-08-9
Correction factor for light activity at work : 6.7/10
Correction factor for difference between human and experimental exposure conditions : 7/5 (In the study, animals were exposed 7 days per week, and workers work 5 days per week).
Oral absorption = 100 % (see section 7.1 Toxicokinetics)
Inhalation absorption = 100% (see section 7.1 Toxicokinetics)
NOAEC = NOAEL x (1/0.38) x (6.7/10) x 7/5= 50 x (1/0.38) x (6.7/10) x 7/5 = 123.4 mg/m3
Dermal NOAEL = oral NOAEL x 100/10 x 7/5= 50 x 100/10 x 7/5 = 700 mg
NOAEC = NOAEL x (1/1.15) = 50 x (1/1.15)
= 43.5 mg/m3
Dermal NOAEL = oral NOAEL x 100/10 = 50 x 100/10 = 500 mg/kg b
Oral absorption is expected to be the same between rodents and humans.
No modification of the dose descriptor is needed.
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