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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental start: 06/06/11 - Experimental end: 10/06/11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
24.37 mg/L
Temp.:
20 °C
pH:
5.84
Remarks on result:
other: Mean values
Water solubility:
23.95 mg/L
Temp.:
20 °C
pH:
6.11
Water solubility:
23.52 mg/L
Temp.:
20 °C
pH:
5.75
Water solubility:
25.65 mg/L
Temp.:
20 °C
pH:
5.67
Details on results:
See "Any other information on results incl. tables".

Water solubility results of each replicate are presented in the following table:

 

 

Sample

 

 

pH

 

Test item concentration measured in each flask, mg/L

 

T24 h

 

 

6.38 – 5.85

23.8 – 24.1

 

T48 h

 

 

5.73 – 5.77

23.45 – 23.6

 

T72 h

 

 

5.75 – 5.59

26.4 – 24.75

 

Average concentration

 

 

-

 

24.37

 

As required by the Guideline, the concentrations measured at each time point do not differ by more than 15 %.

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the test item 1,3 - Diphenyl -2- Thiourea was assessed according to the OECD guideline 105. It was estimated at 24.37 mg/l. During the analysis,the temperature was 20 +/- 0.5°C and the mean value of pH was 5.84.
Executive summary:

The water solubility of the test item 1,3 - Diphenyl -2- Thiourea was assessed according to the OECD guideline 105.


During the analysis,the temperature was 20 +/- 0.5°C and the mean value of pH was 5.84.


The values of the replicates are reported below:


   

























Test



Results



 


Water Solubility


OECD105 – Flask Method



 


pH



 


Water Solubility at 20°C, mg/L


 



TestT24 h


TestT48 h


TestT72 h



6.11


5.75


5.67



23.95


23.52


25.65



Mean value



5.84



24.37



 


 


Based on these values, 1,3 -diethyl-2 -thiourea can be considered as slightly soluble in water.

Description of key information

The water solubility was assessed according to the OECD guideline 105.

Key value for chemical safety assessment

Water solubility:
24.37 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item 1,3 - Diphenyl -2- Thiourea was assessed according to the OECD guideline 105.

During the analysis,the temperature was 20 +/- 0.5°C and the mean value of pH was 5.84.

The values of the replicates are reported below:

  

Test

Results

 

Water Solubility

OECD105 – Flask Method

 

pH

 

Water Solubility at 20°C, mg/L

 

TestT24 h

TestT48 h

TestT72 h

6.11

5.75

5.67

23.95

23.52

25.65

Mean value

5.84

24.37

 

Based on these values,1,3 -diethyl-2 -thiourea can be considered as slightly soluble in water.