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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013-10-23 to 2013-10-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
other: Preliminary test
Specific details on test material used for the study:
- Name of test material (as cited in study report): Dimethyl Piperazine
- Substance type: Clear liquid
- Physical state: Liquid
- Lot/batch No.: 1903-3/2012
Key result
Water solubility:
> 1 000 g/L
Temp.:
20 °C
pH:
6.68
Details on results:
The preliminary estimate resulted in an estimated water solubility of > 1000 g/L.
Miscibility was observed at every stage. The mixing of sample and water was noted to be exothermic.
Conclusions:
The water solubility of the test substance was determined to be > 1000 g/L at 20°C.

Description of key information

In a GLP study according to the preliminary test as specified in test method EC A.6, the test substance was determined to be miscible with water in all proportions under ambient conditions (Younis, 2013). The mixing of sample and water was noted to be exothermic.

Key value for chemical safety assessment

Water solubility:
1 000 g/L
at the temperature of:
20 °C

Additional information

The substance is miscible with water in all proportions. The bounded value of 1000 g/L is used as the key value for chemical safety assessment, although the water solubility was estimated to be > 1000 g/L.