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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013-10-23 to 2013-10-24
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Lot/batch number of test material: 1903-3/2012
- Purity: not indicated
- Appearance: clear liquid
Key result
Water solubility:
> 1 000 g/L
Temp.:
20 °C
pH:
6.68
Details on results:
The preliminary estimate resulted in an estimated water solubility of > 1000 g/L.
Miscibility was observed at every stage. The mixing of sample and water was noted to be exothermic.
Conclusions:
The water solubility of the test substance was determined to be > 1000 g/L at 20°C.

Description of key information

In a GLP study according to the preliminary test as specified in test method EC A.6, the test substance was determined to be miscible with water in all proportions under ambient conditions (Younis, 2013). The mixing of sample and water was noted to be exothermic.

Key value for chemical safety assessment

Water solubility:
1 000 g/L
at the temperature of:
20 °C

Additional information

The substance is miscible with water in all proportions. The bounded value of 1000 g/L is used as the key value for chemical safety assessment, although the water solubility was estimated to be > 1000 g/L.