1,4-dimethylpiperazine

Oxidising properties

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

oxidising liquids

Type of information:

other: Expert statement

Adequacy of study:

supporting study

Study period:

2013-10-24 - 2013-10-29

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Expert statement

Qualifier:

according to guideline

Guideline:

EU Method A.21 (Oxidising Properties (Liquids))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Lot/batch number of test material: 1903-3/2012
- Purity: not indicated
- Appearance: clear liquid

Sample tested:

other: not tested/measured

Remarks:

but based on expert statement

Parameter:

other: examination of structural formula of the test substance

Remarks on result:

other: In every respect of the oxidising liquids exemption procedure, the substance does not show any evidence of possessing oxidising properties.

Remarks:

Hence the test item is not expected to exhibit oxidising properties

Examining the structural formula, the following observations can be made:

- The molecule does not contain any functional groups such as organic nitro compounds, N-halogen compounds (N-X), Oxohalogen compounds, interhalogen compounds

- The highly electronegative atoms which are present constitute a high proportion of the molecule and are bound to elements in a high oxidation state. In case of dimethyl piperazine there are no highly electronegative atoms

- The highly electronegative atoms which are bonded to each other or to other electronegative elements such as iodine, nitrogen, sulphur or phosphorus. In the case of dimethyl piperazine, there are no highly electronegative atoms.

- Assessment against the above criteria indicates strongly that the molecule will not have oxidising properties.

In every aspect of the oxidising liquids exemption procedure, dimethyl piperazine does not show any evidence of possessing oxidising properties.

Interpretation of results:

GHS criteria not met

Conclusions:

On the basis of this exercise, the material should be considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Reference 2

Endpoint:

oxidising liquids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied

Description of key information

Based on the chemical structure, the test substance is determined to be non-oxidising (waiver statement). This conclusion is supported by a theoretical expert assessment (Younis, 2013).

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

The test material should be considered as not oxidising and should not be subjected to experimental testing. The material meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.