1,4-dimethylpiperazine

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

self-heating substances / mixtures

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a liquid

Reference 2

Endpoint:

flammable solids

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the substance is a liquid

Reference 3

Endpoint:

pyrophoric liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2013-10-29

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Lot/batch number of test material: 1903-3/2012
- Purity: not indicated
- Appearance: clear liquid

Key result

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition on contact with air (not further specified)

No ignition or charring was observed during any test. The sample is therefore not pyrophoric.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

No ignition or charring was observed during any test. The sample is therefore not pyrophoric.

Reference 4

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2013-10-24 - 2013-10-29

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Lot/batch number of test material: 1903-3/2012
- Purity: not indicated
- Appearance: clear liquid

Key result

Test procedure:

step 4

Remarks on result:

no reaction with water observed

Test results - Initial tests:

Tests 1, 2 & 3 were not performed due to previous tests indicating that the sample does not react violently with water.

Test results - Final test:

No gas generation or spontaneous ignitions were observed during any of the tests. The samples do not generate flammable gases in contact with water and is therefore non-hazardous.

Comments: An initial, slight increase observed during the gas generation trend is due to the temperature increase observed when the sample is mixed with water.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

No gas generation or spontaneous ignitions were observed during any of the tests. The sample does not generate flammable gases in contact with water and is therefore non-hazardous.

Description of key information

The test substance is concluded not to be pyrophoric, nor flammable in contact with water following GLP studies in accordance with EC test methods A.12 and A.13 (Younis, 2013). The flashpoint was determined to be 20°C at atmospheric pressure. Since the flashpoint is 20°C, the substance is classified as highly flammable.

Key value for chemical safety assessment

Flammability:

flammable

Justification for classification or non-classification

The flash-point of the test substance was determined to be 20 °C at 100.6 kPa and is therefore within the range relevant for classification and labelling under the CLP regulation (<60 °C): the test substance should be classified as a category 2 flammable liquid with hazard statement H225: Highly flammable liquid and vapour (flashpoint < 23 °C and boiling point > 35 °C).

The test substance is concluded not to have pyrophoric properties nor to be flammable in contact with water.