[29H,31H-phthalocyaninato(2-)-kappa4N29,N30,N31,N32]copper, sulfonated, condensed with 2,4- diaminobenzenesulfonic acid and ammonia, converted with sodium hydroxide 2,4,6-trichloro-1,3,5-triazine and ammonium chloride

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Identification: FAT 40045/Z
Lot: AT-2486840

Key result

Water solubility:

ca. 376 g/L

Conc. based on:

test mat.

Temp.:

20 °C

Remarks on result:

other: pH is not specified

Preliminary Visual Estimation of the Water Solubility:

 

Amount of test item in mg	Total volume in ml	Apperance of mixture
100	0.1	Undissolved
	0.5	Dissolved

 

The preliminary visual experiments showed that the water solubility of the test item is > 200 g/l and < 1000 g/l. Therefore the water solubility had to be determined by the “flask method”. Due to the high water solubility it was tested which amount of the test substance could be stirred in a defined volume of water.

 

Volume of water in ml	Mass of the added test item in g	Total mass of the test item in g	Apperance of mixture
8	3.0	3.0	solution is stirrable
8	+0.5	3.5	solution is stirrable
8	+0.5	4.0	could not be stirred

 

Due to this stirring experiment the main test could be performed with 3.5 g in 8 ml water (438 g/l). This solution was stirred at 20 °C for 22 hour. After this time a dark colored pasty solution was observed. No precipitate was observed. The stirring test showed that 438 g/l test item can be used for flask method.

 

Flask-Method:

 

Experiment	A	B	C	D (blank)
Amount of test item (g)	3.5	3.5	3.5	--
Stirring time at 30 °C (h)	24	48	72	72
Aliquot of the flasks μl /10/0.o/40/10	10.0	10.0	10.0	10.0
Measured concentration (μg/ml)	38.6	37.4	37.4	--
Water solubility (g/l)	380	374	374

 

Average experiments A to C: 376 g/l

Standard deviation: 3.5 g/l

Relative standard deviation: 0.9 %

 

Standard	Measured concentration (μg/ml)	Recovery rate
Standard 1 (c=1.37 μg/ml)	1.38	100.7
Standard 2 (c= 6.85 μg/ml)	6.92	101.0
Standard 4 (c= 27.4 μg/ml)	27.2	99.3

 

Recovery range from 99.3 % to 101.0 % indicates a sufficient accuracy of the analytical method.

Conclusions:

The water solubility of the test item at a temperature of 20 °C was determined to be 376 g/l.

Executive summary:

Water solubility of FAT 40045/Z TE was assessed according to the flask method as specified in OECD Guideline 105. In the experiment, three flasks were prepared with 8 ml distilled water and about 3.5 g of the test item. These were stirred for different times at 30 °C (experiment C for 72 h, experiment B for 48 h, experiment A for 24 h) in tightly closed flasks. After 24 h equilibration at 20 °C a dark colored pasty solution was observed.

Based on the findings of the study, the water solubility (cs) of the test item at a temperature of 20 °C was determined to be 376 g/l.

Description of key information

Water solubility of FAT 40045/Z was assessed according to the flask method as specified in OECD Guideline 105.  In the experiment, three flasks were prepared with 8 ml distilled water and about 3.5 g of the test item. These were stirred for different times at 30 °C (experiment C for 72 h, experiment B for 48 h, experiment A for 24 h) in tightly closed flasks. After 24 h equilibration at 20 °C a dark colored pasty solution was observed. Based on the findings of the study, the water solubility (cs) of the test item at a temperature of 20 °C was determined to be 376.0 g/l. 

Key value for chemical safety assessment

Water solubility:

376 g/L

at the temperature of:

20 °C