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EC number: 907-672-2
CAS number: -
In a test performed according to OECD guideline 203 common carp
(Cyprinus carpio) was exposed to dibutyl phenyl phosphate using a Water
Accomodated Fraction approach, the 96 hr LL50 of DBPP for Cyprinus
carpio was shown to be 1.8 mg/L (95% CL 1.0 - 3.2). The NOELR for this
test was 1.0 mg/L.
Short-term toxicity data (96h LC50) on 5 different fish species are available, based on 5 different studies. The most recent study (Goodband and Mullee, 2011) is regarded as key study with and LL50 (96h) of 1.8 mg/L.
Short-term toxicity data (96h LC50) on 5 different fish species are
available, based on 4 different studies. For one additional study, the
14 -day LC50 values are available. The most recent study (Goodband and
Mullee, 2011) is regarded as the key study as this study was performed
according to the most recent guidelines. The LL50 value reported in this
study was the lowest in comparison to the other studies. Nevertheless,
all LC50 values reported in the other studies (Thompson and Forbis,
1978a and 1978b, 1979; Rice and Mastri, 1972 and Koboyashi, 2010) are in
the same range of toxicity (>1 but <10 mg/L). Also the different tests
with rainbow trout show very similar results. In the 14
-day test, loss of equilibrium was studied as endpoint besides mortality
(Thompson and Forbis, 1979). The
LC50 (14 -day) value from that study was 2.4 mg/L and the EC50 (14 -day)
for loss of equilibrium was 1.2 mg/L. The 14-day LC50 is comparable in
value to the 4-day LC50 (see short term effects on rainbow trout from
the same authors), which indicates that the ultimate LC50 is already
reached after 4 days.
Based on these results, it can be concluded that the lowest value, which
is measured for common carp, is the key value for the risk assessment
(LL50 (96h) = 1.8 mg/L)). Although this was measured using a WAF
approach, presenting an LL50 (96h) value rather than a LC50 value it is
reasonable to assume – based on the water solubility of the substance –
that LL50 would be equal to the LC50 for DBPP.
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