Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 907-672-2
CAS number: -
An algal growth inhibition test was carried out with Pseudokirchneriella
subcapitata exposed to dibutyl phenyl phosphate was carried out
according to OECD guideline 201. The 72hr EL50 of DBPP for growth rate
was observed to be 9.6 mg/L (based on the Water Accomodated Fraction)
with a 95% CI of 7.8 - 12 mg/L, the NOELR was 3.2 mg/L (WAF). The 72 hr
EL50 of DBPP for Pseudokirchneriella subcapati for Yield was observed to
be 5.0 mg/L (based on the Water Accomodated Fraction). The NOELR was 3.2
Two algal studies are available, one carried out in 1978 according to then existing guidelines (Hollister and Shuba, 1978) and a recent study (2011) carried out according to existing guidelines and under GLP (Vrijenhoef and Mullee, 2011). The latter study is regarded as the key study and the results from that study is used in further risk assessment.
The results of the
studies are comparable, also taking the different exposure time into
account. Though the setup of the studies was not entirely the same as
were the evaluated of the endpoints. The endpoints of the most recent
study are considered most appropriate for further use in the risk
assessment. The most recent study used a WAF approach, however based on
the water solubility of the substance the EL10/50 and a NOELR, can be
regarded the same as the EC10/50 and NOEC. Therefore, the EC50 (72hr) is
9.6 mg/L, the EC10: 3.5 mg/L and the NOEC: 3.2 mg/L for growth rate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again