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EC number: 907-672-2
CAS number: -
In a study carried out according to Standard Methods for Examination of
Water and Wastewater (American Public Health Association, 1976) and
Methods of Acute Toxicity Tests with Fish, Macroinvertebrates and
Amphibians (US EPA 660 -3 -75 -009, 1975) the Maximum Threshold
Concentration for Daphnia magna exposed to DBPP in a 21 day lifecycle
study was determined. The MTC is considered to be the concentration that
an organism can be exposed to without any negative effects. The
endpoints studied were mortality (day 7,14 and 21), total length (day 7
and 21), number of offspring (day 9, 12, 13, 14, 15, 16, 19, 20, 21) and
percentage of gravid females at day 7.
Mortality was the only endpoint which was significantly affected by the
exposure after 21 days of exposure. Total length at 7 days was slightly
less in the highest concentration compared to the controls, but at 21
days there was no statistical difference (p=0.05) between the different
treatments and the controls for any of the sublethal endpoints. However
a significant nr of the young daphnids died due to exposure to DBPP in
the highest concentration (0.25 mg/L). None of the endpoints, including
mortality, was affected in any of the concentrations up to 0.092 mg/L.
Therefore the study concluded that sublethal endpoints do not give an
accurate representation of the chronic effects of DBPP. Based on these
results, a 21 day EC10 value for survival of 0.106 mg/L was derived
(based on measured concentrations) using DEBTox.
A long-term (21-day) study with Daphnia magna was carried out in 1980 (Altshul et al., 1980) to find the Maximum Tolerable Concentration (MTC) of DBPP for Daphnia magna. The study was carried out according to then existing guidelines and can be regarded as a well-performed study (K2). There were no effects on any of the sublethal endpoints evaluated. Based on the effects on survival (21-days), an EC10 of 0.106 mg/L was determined.
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