Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 907-672-2
CAS number: -
An Ames study was performed to investigate the potential of dibutyl
phenyl phosphate (DBPP) reaction mass to induce gene mutations in the
plate incorporation test (experiment I) and the pre-incubation test
(experiment II) using the Salmonella typhimurium strains TA 1535, TA
1537, TA 98 and TA 100, and the Escherichia coli strain WP2 uvrA.
The assay was performed in two independent exerpiments both with and
without liver microsomal activation. Each concentration, including the
controls, was tested in triplicate. The test item was tested at the
following concentrations in both experiment I and experiment II: 3 - 10
- 33 - 100 - 333 - 1000 - 2500 and 5000 ug/plate.
The plates incubated with the test item showed reduced background growth
in all strains at higher concentrations.
Toxic effects, evident as a reduction in the number of revertants (below
the indication factor of 0,5), occurred in nearly all strains with and
No substantial increase in revertant colony numbers of any of the 5
tester strains was observed following treatment with dibutyl phenyl
phosphate (DBPP) reaction mass at any dose level, neither in the
presence nor absence of metabolic activation mix (S9).
Appropriate reference mutagens were used as positive controls and showed
a distinct increase of induced revertant colonies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again