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EC number: 231-843-4
CAS number: 7758-94-3
No relevant effects
This endpoint is covered by the category approach for soluble iron salts
(please see the section on physical and chemical properties for the
category justification/report format). Testing for this endpoint has
been waived in accordance with column 2 and Annex XI, part 1 and 2,
Information from Literature Searches and earlier Assessment Approaches
The literature reviews of Vangheluwe & Versonnen (2004), Johnson et al.
(2007) and OECD (2007) revealed some data. The results of the studies,
selected as “reliable” by the respective authors are listed in the
following tables. Nonetheless the experiments must be rated “not
reliable” (Klimisch 3) according to the Klimisch et al. (1997) scale due
to methodological objections against testing of aquatic organisms as
concluded in the beginning of this chapter (section „Ecotoxicological
information“). True, intrinsic toxicity of iron kations in aerobic
aquatic test organisms cannot be determined in studies when the
solubility of the dissolved ferric kation (as the ferrous form will
readily be oxidized to ferric species) is exceeded. None of the
experiments found effects at such low levels (depend on pH, section
“water solubility”). Notwithstanding the methodological objections
formally expressed in the waiving argument for the standard aquatic test
organisms, the following data are mentioned for completeness.
Test duration [d]
Concentration [mg/L] #
Comments (Author's Reliability)
Blue green alga
Chow et al. 1998
# Concentration related to iron if not stated otherwise under comments
R3: Not reliable according to the authors (set out in Annex 1, p 56 of
Exposure: s = static
Toxicant analysis: n = not measured.
EC50 [mg Fe/L]
Growth rate at pH 4.4 to 10.5
R1 = Rating by the authors (OECD 2007) referring to the Klimisch et al.
(1997) scale, corrected to Klimisch 3 “not reliable” as discussed above.
Nominal / Measured
FeSO4, FeCl3 Fe(NO3)3
Modified liquid Beijerick’s medium
Physiological and morphological parameters
Becker & Keller 1973
N: Nominal concentration
R3: Not reliable according to the authors (set out in chapter 3.2 of
T: Temperature [°C]
Test duration [days]
[mg /L] #
As FeCl3 (R3)
Rai & Mallick 1992
Pany & Mitra 1998
Rai & Mallick (1992
Growth – stimulation
As Fe(NO3)3 (R3)
As FeCl3; pH 7.5 (R3)
Rai & Chandra 1992
NOEC [mg Fe/L]
No relevant data were reported by Vangheluwe & Versonnen (2004) and OECD
Moreau et al. 1994
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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