Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
231-843-4
CAS no.:
7758-94-3
Index number:
Molecular formula:
Cl2Fe
SMILES:
[Cl-].[Cl-].[Fe++]
InChI:
InChI=1S/2ClH.Fe/h2*1H;/q;;+2/p-2
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
32
Of which contain:
16 impurities relevant for classification
2 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed, causes serious eye damage, may be corrosive to metals and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is harmful to aquatic life with long lasting effects and causes skin irritation.

Breakdown of all 233 C&L notifications submitted to ECHA

Acute Tox. 4 H302
Eye Dam. 1 H318
Met. Corr. 1 H290
Skin Irrit. 2 H315
Aquatic Chronic 3 H412
Skin Sens. 1 H317
Not Classified
Skin Corr. 1B H314
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
Acute Tox. 4 H312
Acute Tox. 4 H332
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss*
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (50% of REACH registrations). A majority of data submitters indicating this property of concern indicate that it may relate to an impurity / additive rather than the substance itself.

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 35 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fertilisers, plant protection products, metal surface treatment products, fillers, putties, plasters, modelling clay and adhesives and sealants.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery) and wood (e.g. floors, furniture, toys).

This substance is used in the following products: laboratory chemicals, pH regulators and water treatment products, fertilisers, water treatment chemicals and metal surface treatment products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: agriculture, forestry and fishing, building & construction work, scientific research and development and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: mineral products (e.g. plasters, cement).

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, closed processes with no likelihood of exposure and mixing in open batch processes.

Other release to the environment of this substance is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following products: pH regulators and water treatment products, metal surface treatment products, water treatment chemicals and fertilisers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, as processing aid, in processing aids at industrial sites and in the production of articles.

This substance is used in the following products: pH regulators and water treatment products, water treatment chemicals, laboratory chemicals and metal surface treatment products.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and scientific research and development. This substance is used for the manufacture of: chemicals, metals, electrical, electronic and optical equipment and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens), handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders) and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: contaminated work clothing should not be allowed out of the workplace; do not eat, drink or smoke when using this product; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Take off contaminated clothing and wash it before reuse. If skin irritation or a rash occurs: get medical advice/attention. If skin irritation occurs: Get medical advice/attention. Immediately call a poison center or doctor/physician. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Rinse the mouth. Follow specific treatment (see label). If swallowed: call a poison center or doctor/physician if you feel unwell. If on skin: wash with soap and water.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Acciaieria Arvedi Spa, Via Acquaviva 18 26100 Cremona Lombardia Italy
  • ALTAIR CHIMICA SPA, VIA MOIE VECCHIE 13 56048 SALINE DI VOLTERRA (PI) Italy
  • ARCELORMITTAL BREMEN GMBH, Carl-Benz-Str. 30 28237 BREMEN Germany
  • Balver Chemieservice GmbH, Buschhausener Strasse 153 46049 Oberhausen Nordrhein- Westfalen Germany
  • Chemische Fabrik Wocklum Gebr. Hertin GmbH & Co. KG, Glärbach 2 58802 Balve Germany
  • Chimcomplex S.A. Borzesti, 3, Industriilor Street 601124 Onesti Bacau Romania
  • Continvest ltd, blvd "Shipchenski Prohod" № 18, Glaxy Trade Center, block D, fl. 5, office 505 1113 Sofia Sofia Bulgaria
  • DEKITRA S.A., Ctra. Miranda de Ebro a Puentelarrá km.5 Pol. Ind. Lantarón 01213 LANTARON Alava Spain
  • Donau Chemie Aktiengesellschaft, Am Heumarkt 10 1037 Vienna Vienna Austria
  • Donauchem Vegyianyag Kereskedelmi Kft, Bányalég u. 37-43 1225 Budapest Hungary
  • EcoloChem Magyaróvár Kft., Timföldgyari u. 13.B.ep 9200 Mosonmagyaróvár Hungary
  • FERI-TRI S.A., INDUSTRIAL SQUARE NO 42 57022 INDUSTRIAL AREA OF THESSALONIKI - SINDOS Greece
  • Global Special Steel Products, SAU, Avda. José Mª Quijano s/nº. 39400 Los Corrales de Buelna. Santander Spain
  • Hörle Wire AB, hörle 33125 värnamo Sweden
  • Iron Service S.r.l., Via Classicana, 45 48122 Ravenna Italy
  • Kemira Germany GmbH, Marie-Curie-Strasse 10 Innovationspark D-51377 Leverkusen Germany
  • Kemira Ibérica S.A., Gran Via Corts Catalanes 641 ES-08010 BARCELONA Spain
  • Kemira Kemi AB, Industrigatan 83 SE-25109 HELSINGBORG Sweden
  • LIBERTY MAGONA S.R.L., Via Pasquale Villari ,39 50136 Firenze Toscana Italy
  • Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
  • Nouryon Industrial Chemicals GmbH, Hauptstraße 47 49462 Ibbenbüren Germany
  • Produits Chimiques de Loos SAS, 22, rue Clémenceau - BP 39 FR-59374 Loos Nord Pas-de-Calais France
  • Ramboll Deutschland GmbH, Werinherstraße 79 Gebäude 32a 81541 München Germany
  • REACH MONITOR SLU , Carrer Orient 78-84 5è, 2a 08072 Sant Cugat del Vallès Spain
  • Salzgitter Flachstahl GmbH, Eisenhuettenstrasse 99 38239 Salzgitter Germany
  • SANIMET spa, Via Quasimodo 19 25020 Flero Brescia Italy
  • Sidra Wasserchemie Bitterfeld GmbH, Parsevalstrasse 06749 Bitterfeld Germany
  • Sidra Wasserchemie GmbH, Zeppelinstrasse 27 49479 Ibbenbueren Germany
  • Tessenderlo Group N.V., Troonstraat 130 BE-1050 Brussel Belgium
  • ThyssenKrupp Steel Europe AG, Kaiser-Wilhelm-Straße 100 47166 Duisburg Germany
  • Umicore Specialty Powders France, 54 Avenue RHIN et DANUBE 38000 GRENOBLE France
  • UNOAERRE INDUSTRIES S.P.A., Strada E n.5 52100 Località San Zeno - AREZZO TUSCANY Italy
  • voestalpine Stahl GmbH, voestalpine-Strasse 3 4020 Linz Oberoesterreich Austria
  • VízTEC Víztechnológiai Zrt., Külterület hrsz 013/68. H-2363 Felsőpakony Pest Hungary
  • Wuppermann Hungary Kft., hrsz. 098/2 9071 Gönyü Hungary
  • Steelstrip services ltd t/a servosteel, Pensnett Road DY1 2HA Dudley West Midlands United Kingdom
  • Tata Steel UK Ltd, 30 Millbank SW1P 4WY London United Kingdom

Substance names and other identifiers

Ferro 66
Other
Ferrous chloride
Other
Ferrous dichloride
Other
Iron chloride (FeCl2)
Other
Iron dichloride
EC Inventory, REACH pre-registration
Iron dichloride
REACH pre-registration, Other
Iron protochloride
Other
Iron(2+) chloride
Other
Iron(II) chloride
Other
Iron(II) chloride (1:2)
Other
Natural lawrencite
Other
Iron chloride (FeCl2)
Other
Cloruro Ferroso
Registration dossier
Consortium description: Iron dichloride (EINECS name), Iron chloride (FeCl2) (CAS Registry Index Name), Ferrous chloride, ferrous dichloride
Registration dossier
dichloroiron
C&L Inventory, Registration dossier
Eisen (II)-chlorid
Registration dossier
Ferrous (ii) Chloride
C&L Inventory
Ferrous Chloride
Registration dossier
Ferrous chloride tetrahydrate
C&L Inventory
Iron (II) chloride
C&L Inventory, Registration dossier
Iron chloride (FeCl2)
C&L Inventory
Iron Dichloride
C&L Inventory, Registration dossier
Iron dichloride
C&L Inventory, Registration dossier
Iron(2+) dichloride
C&L Inventory, Registration dossier
iron(II) chloride
C&L Inventory
Iron(II) chloride
Registration dossier
Iron(II) chloride anhydrous
C&L Inventory
Iron(II) chloride, anhydrous
C&L Inventory
lambda2-iron(2+) dichloride
Other
Servosol
Registration dossier
Altsäure
Registration dossier
Cloruro Ferroso
Registration dossier
Dichlorure de fer
Registration dossier
dicloruro de hierro
Registration dossier
Eisen (2) Chloridlösung
Registration dossier
Eisen (II)- chorid
Registration dossier
Eisenchlorur
Registration dossier
Ferro 66
Registration dossier
Ferrocat FI
Registration dossier
FERROSOL 90
Registration dossier
Ferrous (II) chloride (FeCl2)
Registration dossier
Ferrous chloride
Registration dossier
Ferrous dichloride
Registration dossier
Iron (2+) chloride
Registration dossier
Iron (II) chloride
Registration dossier
Iron chloride (FeCl2)
Registration dossier
Iron dichloride
Registration dossier
Iron(II) chloride
C&L Inventory
Servosol 13
Registration dossier
13478-10-9
CAS number
C&L Inventory
612850-32-5
CAS number
Other
612850-32-5
Deleted CAS number
Other
7758-94-3
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 9 studies submitted
  • 6 studies processed
C Physical state at 20°C and 1013 hPa
Solid (83%), Liquid (17%) [6]
C Form
Crystalline (44%), Other (44%), Powder (11%) [9]
C Odour
Other (67%), Odourless (17%), Pungent (17%) [6]
C Substance type
Inorganic (100%) [6]

Type of Study provided
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 18 studies submitted
  • 3 studies processed
R Melting / freezing point
306 - 677 °C @ 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 5
Supporting study 7 4
Weight of evidence
Other 1
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 17 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 11 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other 3
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Boiling point at 101 325 Pa
1 023 °C

Density

Study results
  • 21 studies submitted
  • 5 studies processed
R Density
3.65 g/cm³ [1]
R Relative density
2.898 - 3.16 @ 18 - 25 °C [4]

Type of Study provided
Studies with data
Key study 5
Supporting study 12 1
Weight of evidence
Other 1 1
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Relative density at 20°C
3.2

Vapour pressure

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
0 Pa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 26 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 23
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2 18
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 8
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Henry's law constant
0 Pa.m³.mol-1 @ 12 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (2)
Intermittent releases (freshwater) No hazard identified (2)
Marine water No hazard identified (2)
Intermittent releases (marine water) No hazard identified (2)
Sewage treatment plant (STP) No hazard identified (2)
Sediment (freshwater) No hazard identified (2)
Sediment (marine water) No hazard identified (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil No hazard identified (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (2)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Insufficient data available (further information necessary)
Acute /short term: (Low hazard (no threshold derived)) -
Local Effects
Long-term: Insufficient data available (further information necessary)
Acute /short term: (Low hazard (no threshold derived)) -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.8 mg/kg bw/day repeated dose toxicity
Acute /short term: (No hazard identified) -
Local Effects
Long-term: (Low hazard (no threshold derived)) -
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Insufficient data available (further information necessary)
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: Insufficient data available (further information necessary)
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.4 mg/kg bw/day repeated dose toxicity
Acute /short term: (No hazard identified) -
Local Effects
Long-term: (Low hazard (no threshold derived)) -
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 20 mg/kg bw/day acute toxicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4
Supporting study 22
Weight of evidence
Other 2
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 10 %

Acute toxicity

Study results
oral
  • 36 studies submitted
  • 6 studies processed
P/RResults
LD50 220 - 2 000 mg/kg bw (rat) [8]
LD50 440 - 1 300 mg/kg bw (mouse) [4]
M/CInterpretations of results
Toxicity Category III [2]

Type of Study provided
oral
Studies with data
Key study 1 5
Supporting study 14
Weight of evidence
Other 2 14
Data waiving
no waivers
inhalation
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
dermal
  • 4 studies submitted
  • 2 studies processed
P/RResults
LD50 881 - 2 000 mg/kg bw (rat) [4]
Discriminating dose 881 - 2 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
other routes
  • 24 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 23
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 500 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 1 100 mg/m³
Dermal route:
No adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 1 13
Weight of evidence
Other 2
Data waiving
no waivers
Study data: eye
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1 1
Supporting study 10
Weight of evidence
Other 2
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other 4
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 14 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 20 - 1 000 mg/kg bw/day [32]

Type of Study provided
Study data: oral
Studies with data
Key study 1 5
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 8 studies submitted
  • 2 studies processed
P/RResults
LOAEL (rabbit): 1.4 mg/m³ air [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
No adverse effect observed NOAEL 125 mg/kg bw/day (subacute, rat)
Inhalation route - local effects:
Adverse effect observed LOAEC 1.4 mg/m³ (subacute, rabbit)

Genetic toxicity

Study results
Study data: in vitro
  • 42 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3 7
Supporting study 8
Weight of evidence
Other 1 23
Data waiving
no waivers
Study data: in vivo
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1 5
Supporting study 1 7
Weight of evidence
Other 10
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1 3
Supporting study
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 20 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 3
Supporting study 10
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: other studies
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 200 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 200 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant