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EC number: 232-304-6
CAS number: 8002-26-4
A complex combination of tall oil rosin and fatty acids derived from acidulation of crude tall oil soap and including that which is further refined. Contains at least 10% rosin.
Distilled Tall Oil was not sensitising to
skin in a guinea pig maximisation test carried out in accordance with
OECD Test Guideline 406 and in compliance with GLP (Huntingdon, 1992a).
Clinical signs: No signs of ill health or
toxicity were recorded.
Intradermal injections: Necrosis was
recorded at sites receiving FCA in test and control animals. Irritation
was seen in test animals at sites receiving Bevacid 25/30, 7.5% v/v in
Alembicol D and slight irritation was observed in control animals
receiving Alembicol D. Topical application: Slight erythema was observed
in test animals following topical application with Bevacid 25/30, as
supplied. Very slight erythema was seen in the control guinea-pigs.
The dermal responses seen in the test
animals were similar to those of the controls.
Only one skin sensitisation study is
available for Distilled Tall Oil. This is a reliable guideline study,
according to OECD Test Guideline 406 and in compliance with GLP
(Huntingdon, 1992a). No positive skin reactions were observed in any
According to the criteria set out in
Regulation 1272/2008 Distilled Tall Oil is not classified as a skin
sensitiser on the basis of a reliable guinea pig maximisation test that
was carried out in accordance with OECD Test Guideline 406 and in
compliance with GLP. There was no evidence of sensitisation in 20 test
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