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EC number: 232-304-6 | CAS number: 8002-26-4 A complex combination of tall oil rosin and fatty acids derived from acidulation of crude tall oil soap and including that which is further refined. Contains at least 10% rosin.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Endpoint:
- dissociation constant
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This value is derived using an accepted calculation method
- Principles of method if other than guideline:
- Structure-based QSAR property prediction by means of linear free energy relationships and molecular orbital properties.
- GLP compliance:
- no
- Remarks:
- QSAR
- Dissociating properties:
- yes
- pKa:
- 4.59 - 4.8
- Conclusions:
- Dissociation constant values for the acid constituents of Distilled Tall Oil was obtained using an accepted calculation method. The result is considered to be reliable.
Referenceopen allclose all
The value of pKa indicates that in the range of pH usually considered relevant to the human body and environment, i.e. pH 2-9, the fatty and resin acids constituents of the substance will ionised. However, the neutrals constituents will tend not to ionised at the relevant environmental pH. The table below gives pKa values for the acids.
Distilled Tall Oil acid constituents |
pKa |
LOW BOILING FATTY ACIDS (<C16) |
4.75 |
C16:1 FATTY ACID |
4.74 |
PALMITIC ACID - (C16 SATURATED) |
4.75 |
C17:0 and C17:0 BRANCHED ACIDS |
4.75 |
OLEIC ACID - (cis - C18:1) and isomers |
4.74 |
ELADIC ACID - (trans - C18:1) |
4.74 |
LINOLEIC ACID (c9,c12) |
4.74 |
CONJ. LINOLEIC ACIDS (18:2) |
4.73 |
PINOLENIC ACID - (C18:3, cis-5,9,12) |
4.73 |
LINOLENIC ACID - (C18:3, c9,c12,c15) |
4.74 |
STEARIC ACID - (C18:0) |
4.75 |
C19:0 ACID |
4.75 |
EICOSANONIC ACID-(C20 SATURATED) |
4.75 |
EICOSENOIC ACID - (C20:1) |
4.74 |
EICOSADIENOIC ACID - (C20:2) |
4.74 |
EICOSATRIENOIC ACID - (C20:3 FA) |
4.73 |
Unknown fatty acids |
4.75 |
ISOPIMARIC ACID |
4.80 |
8,15 ISOPIMARIC ACID/C22 FATTY ACID |
4.64 |
ABIETIC ACID and isomers |
4.77 |
SANDARACOPIMARIC ACID |
4.64 |
DEHYDROABIETIC ACID |
4.67 |
Decarboxylated Rosin acids, MW of 256/258 |
4.77 |
NEOABIETIC ACID |
4.59 |
PALUSTRIC ACID/C24 FATTY ACID |
4.75 |
PIMARIC and/or 8,15-PIMARIC ACID |
4.64 |
Description of key information
The pKa of the acids ionisable constituents of Distilled Tall Oil is predicted using a reliable freely-available method.
Key value for chemical safety assessment
Additional information
No measured data for dissociation constant of Distilled Tall Oil were available. The pKa value (normal conditions) was predicted using SPARC.
While the acids constituents (Fatty and Resin acids) group is ionisable, neutrals constituents such as alcohols are extremely weak acids and only dissociate under strongly basic conditions. In the range of pH usually considered relevant to the human body and environment, i.e. pH 2-9, acid constituents will ionise while the neutrals will be non-ionised. There is no need to conduct further testing.
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