Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute toxicity studies have been conducted in fish, daphnia and algae. In summary, for the aquatic compartment dipropylene glycol methyl ether shows EC50s/LC50s that exceed 1000 mg/l in daphnia (48 hr), fish (96 hr) and algae (7 days). The NOEC for reproduction of Daphnia magna corresponds to the highest concentration tested of 0.5 mg/L in the long-term test, which was set very low considering the low acute toxicity of the substance on Daphnia magna. The low chronic toxicity is highlighted in a freshwater algae test with a NOEC at 1000 mg/L. An activated sludge respiration inhibition test showed an EC50 of 4168 mg/l for micro-organisms. Dipropylene glycol methyl ether is readily biodegradable and has very low potential for bioaccumulation (log Kow <1). According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Hence, long-term testing in aquatic species (fish) can be waived for dipropylene glycol methyl ether.