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EC number: 252-104-2
CAS number: 34590-94-8
Acute toxicity studies have been conducted in fish, daphnia and algae.
In summary, for the aquatic compartment dipropylene glycol methyl ether
shows EC50s/LC50s that exceed 1000 mg/l in daphnia (48 hr), fish (96 hr)
and algae (7 days). The NOEC for reproduction of Daphnia magna
corresponds to the highest concentration tested of 0.5 mg/L in the
long-term test, which was set very low considering the low acute
toxicity of the substance on Daphnia magna. The low chronic
toxicity is highlighted in a freshwater algae test with a NOEC at 1000
mg/L. An activated sludge respiration inhibition test showed an EC50 of
4168 mg/l for micro-organisms. Dipropylene glycol methyl ether is
readily biodegradable and has very low potential for bioaccumulation
(log Kow <1). According to REACH Annex IX requirements, long-term
toxicity testing shall only be considered when the chemical safety
assessment indicates the need for further investigations. Hence,
long-term testing in aquatic species (fish) can be waived for
dipropylene glycol methyl ether.
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